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2019 onward, which is when Lexus redesigned the ES on a longer wheelbase with sharper styling and replaced the old trackpad-only infotainment with a proper touchscreen. A car from that generation is the safer buy over an earlier, pre-facelift example.
The BMW 530 costs about the same and our inspections find fewer body or panel repairs on it than the segment average. The Mercedes C200 is cheaper but runs a higher rate of interior staining in our checks. Inside the Lexus range, the IS350 is a sportier saloon for less money if comfort matters less to you.
Well past 150,000 km on the cars we see. The ES350s we inspect in the UAE run to a median of around 163,000 km with no notable mechanical pattern, which is typical for a naturally aspirated V6 saloon serviced through the Lexus dealer network.
Check the CarSwitch inspection report before you buy — it tells you more about condition than the model year does.