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The S450 is the mild-hybrid six-cylinder badge on Mercedes' flagship saloon, introduced on the W222 generation's 2018 facelift in place of the S400 and carried over onto the current W223 generation launched in 2020. Both use a turbocharged straight-six with an electric boost system rather than a V8.
A current W223-generation car, from 2020 onward, if budget allows — it brought a new cabin, updated driver assistance and a more efficient version of the same hybrid six-cylinder. A late W222-generation S450, from 2018 to 2020, is still a comfortable flagship on the previous platform for less money.
The BMW 530 is similar money and shows prior body or panel repair on 52% of cars against the 64% we would expect for saloons of this age and mileage here. The Mercedes C300 is far cheaper, smaller, and retains 50% after five years, for a buyer who wants the badge without the flagship size.
The S450s we inspect here run to a median of around 100,000 km, modest for a flagship saloon of this age and consistent with regular use rather than heavy commercial duty.
Book the CarSwitch inspection before you buy, since it confirms which generation's electronics and suspension you would actually be inheriting.